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Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management
Sponsor: The Hong Kong Polytechnic University
Summary
The goal of this pilot clinical study is to learn if Lycium barbarum polysaccharide (LBP) supplementation helps manage dry eye disease in adults. It will also learn about the safety of LBP supplementation. The main questions it aims to answer are: 1. Does LBP supplementation improve dry eye symptoms after 12 weeks? 2. Does LBP supplementation improve clinical signs of dry eye disease, such as tear film stability, tear production, and ocular surface staining? Researchers will evaluate changes in dry eye symptoms and eye examination results before and after LBP supplementation. Participants will: 1. Take LBP tablets by mouth twice daily for 12 weeks 2. Visit the clinic at baseline, 4 weeks, and 12 weeks for checkups and eye tests 3. Complete dry eye questionnaires and undergo clinical assessments of tear film, ocular surface health, and related eye measurements
Official title: Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management : A Pilot Study
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-09-14
Completion Date
2027-08-01
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Interventions
Lycium Barbarum Polysaccharide
Participants will take Lycium barbarum polysaccharide tablets orally for 12 weeks. The dosing regimen is two tablets twice daily, for a total of four tablets per day. Each tablet contains Lycium barbarum glycoconjugates, blueberry powder, and grape seed extract.
Locations (1)
The Hong Kong Polytechnic University, School of Optometry, Optometry Clinic
Hong Kong, Hong Kong, Hong Kong