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Continuous Renal Replacement Therapy Circuit Lifespan in Intensive Care Patients
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Summary
The goal of this retrospective observational study is to evaluate how long continuous renal replacement therapy (CRRT) circuits remain in use in adult intensive care unit patients and to describe how CRRT pressure measurements change over time. The main questions it aims to answer are: Are higher maximum and mean transmembrane pressure (TMP) values associated with longer CRRT circuit lifespan? Do time-normalized pressure trajectories and cumulative TMP burden differ between circuits with different lifespans? Do access pressure patterns influence the relationship between pressure measurements and circuit lifespan? Researchers will analyze archived CRRT device log files, including access pressure, filter pressure, effluent pressure, return pressure, and TMP measurements. No additional procedures, interventions, or study visits will be required. No directly identifiable patient information will be included in the analytical dataset.
Official title: Evaluation of Continuous Renal Replacement Therapy Circuit Lifespan in Intensive Care Patients: A Retrospective Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
162
Start Date
2026-09-20
Completion Date
2026-09-21
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Interventions
Archived CRRT Device Log Data
This observational study involves no assigned intervention, treatment, device use, or change in clinical care. The study analyzes archived pressure recordings from CRRT device log files generated during routine clinical care. The analyzed variables include access pressure, filter pressure, effluent pressure, return pressure, and transmembrane pressure. CRRT circuit lifespan is evaluated retrospectively according to the time between the first and last valid pressure recording. No additional procedures or study-related interventions are performed.
Locations (1)
Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital
Yenimahalle, Ankara, Turkey (Türkiye)