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Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems
Sponsor: Colgate Palmolive
Summary
Qualified subjects will be enrolled and randomized to either one of the three study groups described above based on their initial modified gingivitis and plaque scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after three months and six months of product use. All subjects will be followed for adverse events throughout the study.
Official title: Clinical Evaluation of a Stannous Fluoride Toothpaste Versus a 67% Bicarbonate Toothpaste and Colgate Cavity Protection Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems: a Six-month Clinical Study in Italy
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-07-20
Completion Date
2027-01
Last Updated
2026-09-25
Healthy Volunteers
Yes
Conditions
Interventions
0.45% SnF HW with NaF (1450 F)
toothpaste
67% Bicarbonate with NaF (1400 F)
toothpaste
Colgate Cavity Protection Toothpaste
Toothpaste with MFP/NaF (1450 F)
Locations (1)
Clinica Odontoiatrica Montesani
Roma, Rome, Italy