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Corticosteroid for Diabetic Macular Edema (DME) Study
Sponsor: Vanderbilt University Medical Center
Summary
Our current goals include confirming inflammation mediators are biomarkers of DR and DME The Aim of this project is to measure aqueous PGE2 and inflammatory cytokines before and after treatment of DME with intravitreal corticosteroid injections. We want to continue the study for one more year as our initial data analysis from the original INSPIRE study shows a possible direct correlation between aqueous biomarkers and DME. We propose treating the DME with corticosteroid to assess the effect upon the intraocular cytokines with inflammation is suppressed.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-04-07
Completion Date
2029-03
Last Updated
2026-09-28
Healthy Volunteers
Yes
Interventions
Intravitreal dexamethasone implant
intravitreal dexamethasone 0.7mg implant
Intravitreal dexamethasone implant
fluocinolone acetonide 0.19mg implant
Locations (1)
Vanderbilt Eye Institute
Nashville, Tennessee, United States