Clinical Research Directory

Inclusion Criteria: 1. Aged 18-60 years, with no gender restrictions. 2. Free from severe systemic diseases. 3. Patients who have undergone stereoelectroencephalography electrode implantation. 4. Patients who have been informed of potential risks, consented to participate in this study, and signed the informed consent form. 5. Daytime clinic blood pressure fluctuates within the following range: 90 mmHg \< systolic blood pressure \< 140 mmHg; 60 mmHg \< diastolic blood pressure \< 90 mmHg. Exclusion Criteria: 1. Patients with scalp electrode hematoma or sub-electrode effusion after intracranial electrode implantation, who are unable to receive electrical stimulation. 2. Patients with intracranial structural lesions (e.g., encephalomalacia foci, vascular malformations, space-occupying lesions, etc.). 3. Pregnant women. 4. Patients who are unable to cooperate due to mental disorders or other causes. 5. Patients who have participated in other clinical trials within the past 3 months. 6. Patients who apply to withdraw from this clinical trial for any reason. 7. Patients with cardiac or pulmonary insufficiency. 8. Patients with white coat effect are excluded. 9. Patients with low cerebrovascular risk assessed by cranial magnetic resonance imaging (MRI).