Labor Characteristics and Maternal-Infant Outcomes in Preterm Primiparous Women

COMPLETED

NCT07844499

Sponsor: Maternal and Child Health Hospital, Jiading District

Summary

This retrospective observational study evaluates labor characteristics in primiparous women with spontaneous preterm birth at different gestational ages and examines their associations with maternal and neonatal outcomes. Medical records of women who delivered at Shanghai Jiading District Maternity and Child Health Care Hospital between January 1, 2020, and December 31, 2025, are reviewed. Participants are classified according to gestational age at delivery into very preterm (28 to 31+6 weeks), moderate preterm (32 to 33+6 weeks), and late preterm (34 to 36+6 weeks) groups. The study compares the onset and duration of the active phase of labor, cervical dilation rate, and durations of the first and second stages of labor across these gestational-age groups. The study also evaluates the associations between labor duration and maternal and neonatal outcomes, including postpartum blood loss, mode of vaginal delivery, and 5-minute Apgar score. The findings are intended to provide evidence for gestational age-specific and individualized labor management in women with spontaneous preterm birth.

Official title: Labor Characteristics of Primiparous Women With Spontaneous Preterm Birth at Different Gestational Ages and Their Association With Maternal and Infant Outcomes

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

OBSERVATIONAL

Enrollment

436

Start Date

2020-01-01

Completion Date

2025-12-31

Last Updated

2026-09-28

Healthy Volunteers

No

Conditions

Preterm Birth

Interventions

OTHER

Gestational Age at Delivery

Gestational age at delivery was the primary exposure of interest. Participants were retrospectively classified into three groups according to gestational age at delivery: very preterm (28 weeks 0 days to 31 weeks 6 days), moderate preterm (32 weeks 0 days to 33 weeks 6 days), and late preterm (34 weeks 0 days to 36 weeks 6 days). No study-specific intervention was assigned, and all exposure and outcome information was obtained from existing medical records.

Locations (1)

Maternal and Child Health Hospital, Jiading District

Shanghai, Shanghai Municipality, China

Clinical Research Directory