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NOT YET RECRUITING
NCT07844681
NA

Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision

Sponsor: University of Minnesota

View on ClinicalTrials.gov

Summary

This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide local excision. Adult participants undergoing Mohs micrographic surgery or wide local excision for skin cancer with a surgical defect suitable for linear repair will be stratified by suture type and randomized to standardized running epidermal suture closure with or without cyanoacrylate skin adhesive. The primary outcome is surgical site infection within 30 days after surgery. Secondary outcomes include scar quality, treatment satisfaction, wound care burden, wound healing characteristics, antibiotic use, culture results, health care utilization related to wound concerns, and adverse events.

Official title: A Prospective Randomized Study of Surgical Site Infection After Linear Repair With or Without Cyanoacrylate Skin Adhesive Following Mohs Micrographic Surgery and Wide Local Excision

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2026-10-01

Completion Date

2029-03-30

Last Updated

2026-09-28

Healthy Volunteers

No

Interventions

DEVICE

Cyanoacrylate Skin Adhesive

Cyanoacrylate skin adhesive will be applied in a thin, continuous layer along the repaired wound after hemostasis and epidermal closure are complete. The adhesive is an FDA-approved topical wound closure product used within its labeled indication.

PROCEDURE

Fast Gut Running Epidermal Suture Closure

Standardized running epidermal closure will be performed using fast gut absorbable suture material after Mohs micrographic surgery or wide local excision.

PROCEDURE

Vicryl Rapide Running Epidermal Suture Closure

Standardized running epidermal closure will be performed using Vicryl Rapide absorbable suture material after Mohs micrographic surgery or wide local excision.

PROCEDURE

Prolene Running Epidermal Suture Closure

Standardized running epidermal closure will be performed using Prolene non-absorbable suture material after Mohs micrographic surgery or wide local excision.

Locations (3)

Oxboro Dermatology Clinic

Minneapolis, Minnesota, United States

University of Minnesota Dermatologic Surgery Clinic - CSC

Minneapolis, Minnesota, United States

University of Minnesota Dermatologic Surgery Clinic - MG

Minneapolis, Minnesota, United States