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Effect of Subperiosteal Ropivacaine After Third Molar Extraction
Sponsor: University of Zagreb
Summary
This study examined whether an additional injection of the long-acting local anesthetic ropivacaine at the surgical site could reduce pain and improve recovery after removal of lower wisdom teeth. Adults aged 18 to 65 years who needed both lower wisdom teeth removed could take part. Each participant underwent two separate wisdom tooth removal procedures, approximately two weeks apart. After one procedure, ropivacaine was injected near the surgical area, while after the other procedure, a sterile saline solution was given in the same way for comparison. Neither the participant nor the surgeon knew which treatment was used at each procedure. Participants recorded their pain after surgery and their use of pain-relieving medication. Mouth opening and the effect of the procedure on daily life and oral health-related quality of life were also assessed. The purpose of the study was to determine whether adding ropivacaine at the surgical site could provide better pain relief and postoperative recovery than standard treatment alone.
Official title: Effect of Supplementary Subperiosteal 0.75% Ropivacaine on Postoperative Outcomes After Mandibular Third Molar Extraction: a Randomized, Split-mouth Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-10-02
Completion Date
2024-08-26
Last Updated
2026-09-28
Healthy Volunteers
Yes
Interventions
Ropivacaine 0.75%
Following surgical extraction and suturing of the mandibular third molar, 2 mL of 0.75% ropivacaine was administered as a supplementary subperiosteal injection at the buccal aspect of the extraction site, slightly apical to the bony socket.
Saline (0.9% NaCl)
Following surgical extraction and suturing of the mandibular third molar, 2 mL of 0.9% sterile saline was administered as a supplementary subperiosteal injection at the buccal aspect of the extraction site, slightly apical to the bony socket.
Locations (1)
Stomatološka poliklinika Zagreb
Zagreb, Croatia