Clinical Research Directory

Inclusion Criteria: 1. Adult (≥ 18 years) with diagnosis of obstructive sleep apnea (AHI ≥ 5/h). 2. Current use of a ResMed or SomnoMed MAD for at least 3 months with reported adherence ≥ 4 hours/night. 3. Ability and willingness to stop using the current MAD for a two-week wash-out period. 4. Agrees to be informed on incidental findings 5. Capable of giving informed consent. Exclusion Criteria: 1. Predominant central sleep apnea. 2. Known temporo-mandibular joint disorders or significant dental conditions that preclude MAD use. 3. Recent dental surgery (\< 1 month) or planned during the investigation. 4. Known pregnancy, breastfeeding or planning pregnancy during the study; 5. Professional drivers or occupations requiring constant vigilance (due to risk of increased sleepiness during wash-out). 6. Participation in another interventional trial or use of medications affecting sleep (sedative/hypnotic agents, opioids, muscle relaxants).