Clinical Research Directory

Inclusion Criteria: 1. Adults ≥18 years of age. 2. Have a history of glaucoma or ocular hypertension. 3. Currently being treated with a preserved topical glaucoma medication and currently have well-controlled intraocular pressure (≤ 21 mmHg). 4. Currently using any type of prostaglandin analog glaucoma monotherapy. 5. Have a history of dry eye disease for at least the past 6 months. 6. Have dry eye disease as determined by the following: Eye Dryness VAS score of ≥40 plus OSDI ≥23 (moderate to severe) plus TBUT \<10 seconds.8, 9 7. Have corrected distance visual acuity of 20/40 or better. 8. Willing to discontinue contact lens wear 24 hours prior to screening visit and throughout the study. Exclusion Criteria: 1. Aqueous deficient dry eye disease as defined by Schirmer's test \<10 mm. 2. Have a systemic health condition that is known to alter tear film physiology (e.g., primary and secondary Sjögren's syndrome). 3. Have a history of ocular surgery within the past 12 months. 4. Have a history of severe ocular trauma, active ocular infection or inflammation that is not dry eye related. 5. Punctal plugs in place for \<3 months and/or Lacrifill in place for \>5 months. 6. Have ever used Accutane. 7. Currently using other ocular medications, including topical anti-inflammatory drops at the time of enrollment. 8. Are pregnant or breast feeding. 9. Have had a physical meibomian gland treatment withing 1 month of enrollment. 10. Initiated, discontinued, or changed dose of a systemic medication known to cause ocular drying (e.g., antihistamines or tricyclic antidepressants) within 14 days of the screening visit. 11. Have a condition or be in a situation, which in the investigator's opinion, may put the participant at significant risk, may confound the results, or may significantly interfere with their study participation.