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NOT YET RECRUITING
NCT07845578
PHASE1

A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight

Sponsor: Novo Nordisk A/S

View on ClinicalTrials.gov

Summary

The purpose of the study is to determine the effect of semaglutide on gastric emptying in people with obesity. Participants will receive either semaglutide or placebo, and the treatment assigned will be decided by chance. Semaglutide is a medicine that doctors can already prescribe, while placebo contains no active medicine.

Official title: An Investigation of the Effect of High Dose s.c. Semaglutide on Gastric Emptying in Participants With Obesity

Key Details

Gender

All

Age Range

18 Years - 64 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-09-25

Completion Date

2027-09-11

Last Updated

2026-09-29

Healthy Volunteers

No

Interventions

DRUG

Semaglutide

Semaglutide will be administered in the thigh, abdomen, or upper arm of body part.

DRUG

Placebo semaglutide

Placebo matched to semaglutide will be administered in the thigh, abdomen, or upper arm of body part.

DRUG

Paracetamol

Paracetamol is administered orally as part of a standardised meal to assess gastric emptying through pharmacokinetic evaluation.

Locations (1)

Medical University of Graz

Graz, Austria