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A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight
Sponsor: Novo Nordisk A/S
Summary
The purpose of the study is to determine the effect of semaglutide on gastric emptying in people with obesity. Participants will receive either semaglutide or placebo, and the treatment assigned will be decided by chance. Semaglutide is a medicine that doctors can already prescribe, while placebo contains no active medicine.
Official title: An Investigation of the Effect of High Dose s.c. Semaglutide on Gastric Emptying in Participants With Obesity
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-09-25
Completion Date
2027-09-11
Last Updated
2026-09-29
Healthy Volunteers
No
Conditions
Interventions
Semaglutide
Semaglutide will be administered in the thigh, abdomen, or upper arm of body part.
Placebo semaglutide
Placebo matched to semaglutide will be administered in the thigh, abdomen, or upper arm of body part.
Paracetamol
Paracetamol is administered orally as part of a standardised meal to assess gastric emptying through pharmacokinetic evaluation.
Locations (1)
Medical University of Graz
Graz, Austria