Clinical Research Directory
Browse clinical research sites, groups, and studies.
ITM vs ITM+Clonidine for Lumbar Fusions
Sponsor: MaineHealth
Summary
Dr. Parker Merrill (anesthesiologist) and Dr. Chris Neal (neurosurgeon) are working on a research study comparing two methods of pain control for patients having spinal fusion surgery. We are looking for English-speaking patients between 18 and 70 years old who are scheduled for 1-2 level lumbar spine fusion surgery. Participants in this study will either get morphine injected during surgery (current pain treatment) or morphine and another drug, clonidine. There is an equal chance of getting the two treatment options. No matter which group you are assigned to, you will be provided with additional pain medication if needed after your surgery. You may not directly benefit from participating in this study, but you might have an improvement in your pain after surgery. You will also be helping researchers and doctors find better pain control options for future patients.
Official title: Intrathecal Morphine vs Intrathecal Morphine Combined With Clonidine for 1-2 Level Lumbar Fusion
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2026-10-01
Completion Date
2028-01-30
Last Updated
2026-10-05
Healthy Volunteers
No
Conditions
Interventions
Intrathecal Morphine + Intrathecal Clonidine
Participants in the intervention group will receive the standard of care (150 mcg of intrathecal morphine) with the addition of 75 mcg of clonidine.
Intrathecal Morphine
Participants in this group will receive the standard of care; 150 mcg of intrathecal morphine
Locations (1)
MaineHealth Maine Medical Center-Portland
Portland, Maine, United States