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vNOTES Versus Vaginal Hysterectomy for Benign Gynecologic Indications
Sponsor: Hatice Nur ÖZGEN
Summary
This randomized non-inferiority trial aims to compare early and late postoperative outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy and vaginal hysterectomy in women undergoing hysterectomy for benign gynecological indications. Eligible participants will be randomly assigned to either vNOTES hysterectomy or vaginal hysterectomy. The primary outcome is postoperative pain at 24 hours measured by the Visual Analog Scale (VAS). Secondary outcomes include postoperative recovery, complications, length of hospital stay, return of bowel function, urinary catheter duration, readmission, and recovery index scores. The study will be conducted at Harran University Hospital.
Official title: Comparison of Early and Late Postoperative Outcomes of vNOTES and Vaginal Hysterectomy in Benign Gynecological Indications: A Randomized Non-Inferiority Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-04-20
Completion Date
2027-12-31
Last Updated
2026-09-29
Healthy Volunteers
No
Conditions
Interventions
vNOTES Hysterectomy
Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy performed for benign gynecologic indications. The procedure is conducted through a transvaginal endoscopic approach without abdominal incisions and is compared with conventional vaginal hysterectomy.
Vaginal Hysterectomy
Conventional vaginal hysterectomy performed for benign gynecologic indications using the standard vaginal surgical approach.
Locations (1)
Harran University Hospital
Sanliurfa, Şanlıurfa, Turkey (Türkiye)