Clinical Research Directory
Browse clinical research sites, groups, and studies.
Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair
Sponsor: Oslo University Hospital
Summary
This prospective, randomized, double-blinded controlled trial will investigate the effectiveness of a lateral quadratus lumborum (QL) block in 50 children aged 6-14 years undergoing iliac crest bone grafting for cleft alveolus repair. Participants will receive either a lateral QL block with bupivacaine and adrenaline or a sham skin puncture. The study will primarily assess postoperative pain at the iliac crest donor site. Secondary outcomes include pain during mobilization, pain at the alveolar surgical site, opioid consumption, time to first rescue analgesia, objective mobilization measured with activity monitors, time to hospital discharge, and adverse events. The study aims to determine whether QL block provides clinically relevant postoperative analgesia while facilitating earlier mobilization and potentially reducing hospital stay in this pediatric population.
Official title: Effectiveness of Quadratus Lumborum Block in Reducing Postoperative Pain, Enhancing Mobilization, and Shortening Hospital Stay in Children Undergoing Iliac Bone Harvest for Cleft Alveolus Repair- a Prospective Randomized Controlled Study
Key Details
Gender
All
Age Range
6 Years - 14 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-09-01
Completion Date
2028-03-01
Last Updated
2026-09-29
Healthy Volunteers
No
Conditions
Interventions
Lateral quadratus lumborum block
A lateral QL blocks will be performed on the site of bone graft. An ultrasound system with a linear array transducer will be used for the QL block procedure. A sterile skin scrub will be performed before needle insertion. The ultrasound coated injection needle will be advanced until the needle tip is positioned between the aponeurosis of the transversus abdominis muscle and the pararenal fat close to the quadratus lumborum muscle. Following aspiration, 0.3 ml/kg of bupivacaine 2.5 mg/ml with adrenaline 5 mcg/ml will be injected.
Sham Block
Only a skin puncture will be performed
Locations (1)
Oslo University Hospital
Oslo, Norway