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BRCC36 and Telomerase Levels in Women With Polycystic Ovary Syndrome
Sponsor: Cumhuriyet University
Summary
This prospective observational case-control study evaluated serum BRCC36 and telomerase (TE) levels in women with polycystic ovary syndrome (PCOS) and healthy controls. Women aged 18-43 years were included. The study comprised 30 women diagnosed with PCOS according to ESHRE/ASRM criteria and 30 healthy women with regular menstrual cycles. A single 5-mL venous blood sample was collected from each participant. Serum was separated by centrifugation and stored at -80°C until analysis. Serum BRCC36 and telomerase levels were measured using commercially available enzyme-linked immunosorbent assay (ELISA) kits. The study evaluated differences in these biomarkers between women with PCOS and healthy controls and their relationships with clinical and biochemical characteristics.
Official title: Evaluation of Serum BRCC36 and Telomerase Levels in Women With Polycystic Ovary Syndrome
Key Details
Gender
FEMALE
Age Range
18 Years - 43 Years
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2024-02-20
Completion Date
2026-05-01
Last Updated
2026-09-30
Healthy Volunteers
Yes
Conditions
Locations (1)
Sivas Cumhuriyet University
Sivas, Sivas, Turkey (Türkiye)