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NOT YET RECRUITING
NCT07849712
NA

An Exploratory Clinical Study Of Bempemab Combined With Anlotinib As First-Line Treatment For Elderly Patients With Locally Advanced Or Metastatic Non-Small-Cell Lung Cancer

Sponsor: Zhejiang Cancer Hospital

View on ClinicalTrials.gov

Summary

This exploratory clinical study evaluates the efficacy and safety of combining benmelstobart (a PD-L1 inhibitor) with anlotinib (a multi-target anti-angiogenic TKI) as a first-line, chemotherapy-free treatment for elderly patients with locally advanced or metastatic non-small cell lung cancer (NSCLC).

Official title: Bemo-sufail Monoclonal Antibody Combined With Anlotinib As First-Line Treatment For Elderly Patients With Locally Advanced Or Metastatic Non-Small-Cell Lung Cancer: An Exploratory Clinical Study

Key Details

Gender

All

Age Range

75 Days - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-10-01

Completion Date

2028-12-31

Last Updated

2026-09-30

Healthy Volunteers

No

Interventions

DRUG

Benmelstobart Combined With Anlotinib

Benmelstobart: Administered via intravenous infusion at a dose of 1200 mg every 3 weeks (Q3W). Anlotinib Hydrochloride: Administered orally at a dose of 10 mg daily, taken for 2 consecutive weeks followed by 1 week off, in repeated 3-week (21-day) cycles.

Locations (1)

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China