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Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis
Sponsor: Ziauddin University
Summary
This study aims to compare the effectiveness of irrigation of 0.5% bupivacaine versus normal saline at the gallbladder surgical bed in reducing postoperative pain following laparoscopic cholecystectomy for acute cholecystitis. Postoperative pain remains a common concern despite the minimally invasive nature of laparoscopic surgery. The study evaluates pain intensity at 4, 8, and 12 hours after surgery using the Visual Analogue Scale (VAS).
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2025-10-01
Completion Date
2026-04-30
Last Updated
2026-10-01
Healthy Volunteers
No
Conditions
Interventions
Bupivacaine 0.5%
20 mL of 0.5% bupivacaine irrigated over the gallbladder bed through the lateral-most port after specimen retrieval, before desufflation and port closure.
Normal Saline 0.9%
20 mL of 0.9% sodium chloride irrigated over the gallbladder bed using the same technique and timing as the bupivacaine group.
Locations (1)
Dr. Ziauddin Hospital
Karachi, Sindh, Pakistan