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Clinical Outcomes of Root Canal Treatment Using Modern Irrigation Protocols
Sponsor: University of Illinois at Chicago
Summary
Post-operative pain remains a frequent complication after root canal treatments. This clinical trial evaluates the post-operative outcome following endodontic treatments using four irrigation approaches: conventional needle irrigation, GentleWave®, EdgePRO™, and Fotona LightWalker®. The study will assess patients' post-operative pain and other symptoms following treatment, as well as healing of the tissues around the treated tooth over time.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-09
Completion Date
2028-10
Last Updated
2026-10-01
Healthy Volunteers
No
Conditions
Interventions
GentleWave®
An advanced endodontic irrigation system that utilizes a vortex of fluids and acoustic energy that cleans the deepest, most complex portions of the root canal system. Regulatory approval status: FDA cleared Post-operative pain information will be collected via phone interview. Complications and adverse effects are the same as with other systems of similar design and traditional root canal therapy, and may include sensitivity, inflammation, and pain.
EdgePRO™
An advanced endodontic irrigation system that delivers Laser Light Sound Energy at a specific wavelength and frequency to the irrigants in the canal to form Cavitation Waves throughout the root canal system. This allows optimal cleaning, debridement, and disinfection of the root canal system. Regulatory approval status: FDA cleared Post-operative pain information will be collected via phone interview. Complications and adverse effects are the same as with other systems of similar design and traditional root canal therapy, and may include sensitivity, inflammation, and pain.
Fotona LightWalker®
An advanced endodontic irrigation system that combines Er:YAG and Nd:YAG wavelengths to optimize pulse control, intuitive interface, and minimally invasive approach to enhance patient outcomes, improve efficiency, and expand clinical capabilities. Regulatory approval status: FDA cleared Post-operative pain information will be collected via phone interview. Complications and adverse effects are the same as with other systems of similar design and traditional root canal therapy, and may include sensitivity, inflammation, and pain.
Conventional Needle Irrigation
Conventional needle irrigation is the traditional method that uses a syringe and needle to deliver irrigation solutions into the root canal system to flush out tissue and debris in endodontic therapy. Post-operative pain information will be collected via phone interview. Complications and adverse effects are the same as with other systems of similar design and traditional root canal therapy, and may include sensitivity, inflammation, and pain.
Locations (1)
University of Illinois Chicago, College of Dentistry, Department of Endodontics
Chicago, Illinois, United States