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Mailed FIT-Based Outreach Interventions
Sponsor: National Cancer Centre, Singapore
Summary
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for average-risk adults aged 50-75, only 44.9% of eligible individuals are up to date with CRC screening. Screening participation, adherence to repeat annual FIT, and completion of diagnostic colonoscopy after abnormal FIT results remain suboptimal. This study aims to identify the most effective and cost-effective strategy for increasing CRC screening participation and adherence.
Official title: Mailed FIT-Based Outreach Interventions vs Usual Care to Increase Uptake of Colorectal Cancer Screening in a Multi-Ethnic Population: A 7-Arm Randomized Controlled Trial
Key Details
Gender
All
Age Range
50 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40000
Start Date
2026-10-30
Completion Date
2030-10-30
Last Updated
2026-10-01
Healthy Volunteers
Yes
Conditions
Interventions
SMS Reminders
5,000 patients will be allocated in this arm.
SMS reminders + mailed reminder
5,000 patients will be allocated in this arm.
SMS reminders + mailed reminder + patient navigation
5,000 patients will be allocated in this arm.
SMS reminders + mailed return
5,000 patients will be allocated in this arm.
SMS reminders + mailed FIT
5,000 patients will be allocated in this arm.
SMS reminders + mailed FIT + patient navigation
5,000 patients will be allocated in this arm.
Locations (5)
SingHealth Polyclinic
Singapore, Singapore
National Cancer Center, Singapore
Singapore, Singapore
Changi General Hospital
Singapore, Singapore
Sengkang General Hospital
Singapore, Singapore
Singapore General Hospital
Singapore, Singapore