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AI-Assisted 3D Reconstruction for Lung Resection Planning
Sponsor: S. Andrea Hospital
Summary
This prospective observational study aims to validate an artificial intelligence (AI)-based system for automated three-dimensional (3D) reconstruction of pulmonary anatomy from preoperative chest computed tomography (CT) scans in patients undergoing lung resection. The AI system will automatically identify and reconstruct relevant pulmonary anatomical structures, including pulmonary arteries, veins, bronchi, lobes, and segments. AI-generated 3D reconstructions will be compared with expert manual 3D reconstructions and with anatomical findings documented during surgery. The primary objective is to assess the anatomical accuracy of AI-generated 3D reconstructions in identifying surgically relevant bronchovascular anatomy and anatomical variants. Secondary objectives include evaluating accuracy for individual anatomical structures, discrepancies between automated and manual reconstructions, concordance with intraoperative findings, and the time required to generate and review the automated reconstruction. The study is observational and will not modify the planned surgical procedure or standard patient care.
Official title: Prospective Validation of an Artificial Intelligence-Based 3D Reconstruction Model for Preoperative Planning of Lung Resection.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2026-11-02
Completion Date
2027-08-01
Last Updated
2026-10-01
Healthy Volunteers
No
Interventions
AI-Based 3D Reconstruction
Preoperative contrast-enhanced chest CT images will be processed using an artificial intelligence-based segmentation system to automatically generate three-dimensional reconstructions of pulmonary anatomy, including pulmonary arteries, veins, bronchi, lobes, and segments when applicable. The AI-generated reconstructions will be evaluated against expert manual 3D reconstruction and intraoperative anatomical findings. The AI output will not determine or modify the planned surgical treatment.
Locations (1)
Azienda Ospedaliera Universitaria Sant'Andrea
Rome, Lazio, Italy