Clinical Research Directory

Inclusion criteria 1. Received invasive mechanical ventilation for ≥ 48 hours; 2. Aged ≥ 21 years; 3. Premorbidly independent in basic activities of daily living; 4. Had decision-making capacity before the acute illness and are expected to regain capacity before acute hospital discharge; 5. Have evidence of new or worsening physical, cognitive, mental-health or swallowing impairment compared with their premorbid state; and 6. Are ultimately planned for discharge to the community/home setting. Worsening in PICS domains is defined as an increase in CFS score compared with premorbid status, newly acquired swallowing dysfunction, new cognitive impairment after exclusion of delirium, suspected anxiety or depressive symptoms, or clinically important deterioration in physical or functional performance. Mental-health screening will not be interpreted as diagnostic criteria for anxiety or depressive disorders. Exclusion criteria * cognitive or psychiatric impairment that precludes meaningful participation in the study; * are already enrolled in, or expected to enter, a structured follow-up pathway that substantially duplicates the rehabilitation intervention; or * have treatment primarily directed towards palliation or end-of-life care