Clinical Research Directory

Outcomes and Inter-Stage Interval in Staged Bilateral PCNL

Sponsor: Ankara Training and Research Hospital

Summary

This prospective, single-center observational study evaluated patients undergoing staged bilateral standard percutaneous nephrolithotomy (PCNL) for bilateral renal stones. Each participant underwent PCNL on one kidney followed by contralateral PCNL in a separate session, allowing a paired within-patient comparison in which each patient served as their own control. The study aimed to compare operative, hematologic, renal, inflammatory, stone-free, and complication outcomes between the first and second PCNL procedures. In addition, the association between the inter-stage interval and second-side outcomes was explored, with particular emphasis on systemic inflammatory response assessed using neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII).

Official title: Within-patient Comparison of First- Versus Second-side Outcomes and the Effect of the Inter-stage Interval in Staged Bilateral Percutaneous Nephrolithotomy: a Prospective Single-center Study

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