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Summary
The vagus nerve is a nerve that controls many bodily functions, including stomach function. Investigators hope that electrically stimulating the nerve around the external ear will also stimulate the internal vagus nerve. If it does, then investigators hope that this may lead to additional treatment options for patients with nausea and vomiting and disordered stomach function. The overall purpose of the ABVN Phase 2 grant is to expand on previous work evaluating the effects of noninvasive stimulation on vagal nerve function. This will be accomplished through several independent, but related, studies. In this study, investigators will evaluate the effect of percutaneous electrical field stimulation on the vagus nerve in healthy subjects. \[This study was originally described in NCT06491758, however a separate record has been created to more accurately reflect the independence of the individual studies supported by the ABVN 2 grant.\]
Official title: Effect of Electrical Stimulation of the Auricular Branch of the Vagus Nerve (ABVN) on Cervical Vagus Nerve Action Potentials (CNAPs) Phase 2 - Ear Stimulation
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
23
Start Date
2021-10-08
Completion Date
2022-06-09
Last Updated
2026-10-02
Healthy Volunteers
Yes
Conditions
Interventions
Percutaneous Electrical Nerve Field Stimulation (PENFS)
The PENFS is a battery-operated micro-stimulation appliance weighing 5 grams designed as a disposable product for single use. It is placed behind the patient's ear and connected to stimulation needles on the auricle. The appliance transmits low-frequency electrical impulses.
Locations (1)
Indiana University
Indianapolis, Indiana, United States