Clinical Research Directory

Inclusion Criteria: * Patients aged 18 to 45 years. * Classified as ASA physical status I or II. * Indicated for minor oral surgical procedures, such as impacted mandibular third molar removal, alveoloplasty, or periapical surgery. * Presence of healthy surrounding soft tissues at the surgical site. * Willingness to participate and provide written informed consent. * Ability to comply with postoperative follow-up visits. Exclusion Criteria: * Systemic diseases known to impair wound healing, including uncontrolled diabetes mellitus, immunocompromised states, autoimmune disorders, and chronic renal or hepatic disease. * Bleeding disorders or use of anticoagulant/antiplatelet therapy. * Chronic corticosteroid or immunosuppressive therapy. * Active local infection at the surgical site. * History of smoking or smokeless tobacco use within the past 6 months. * Pregnant or lactating women. * Known hypersensitivity to cyanoacrylate or suture materials. * Poor oral hygiene, defined clinically by visible plaque accumulation and gingival inflammation. * Patients requiring bone grafting, membrane placement, or complex flap designs.