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Clinical Lid Eradication of Antifungal-Responsive FUNGUS Study
Sponsor: Brent Kramer
Summary
The goal of this clinical trial is to learn if Natacyn works to reduce or eliminate laboratory-confirmed fungal organisms in subjects with fungal-positive blepharitis identified in a previous study. asthma in adults. It will also learn more about the safety of Natacyn. The main questions it aims to answer are: Does Natacyn reduce or eliminate fungal presence? Does Natacyn cause a reduction in eye irritation and itchiness? What medical problems do participants have when using Natacyn? Participants will: Apply Natacyn 4 times a day for 21 days Visit the clinic once every week for checkups and tests Keep a diary of the number of times they apply Natacyn over the 21-day period
Official title: Treatment of Fungal Blepharitis With Natacyn: A Prospective Interventional Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-10
Completion Date
2027-03
Last Updated
2026-10-02
Healthy Volunteers
No
Conditions
Interventions
NATACYN®
Natamycin 5% ophthalmic suspension (Natacyn®) is FDA-approved for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms (NATACYN US Prescribing Information). The route of administration in this study - application to the eye at a frequency of QID for 21 days - is consistent with the labeled dosing range for fungal blepharitis (one drop, 4 to 6 times daily).
Locations (5)
The Eye Associates
Jacksonville, Florida, United States
Kannarr Eye Care
Pittsburg, Kansas, United States
Pure Ophthalmic Research
Mint Hill, North Carolina, United States
CORE Inc.
Shelby, North Carolina, United States
Vance Thompson Vision
Sioux Falls, South Dakota, United States