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Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
Sponsor: University of Zagreb
Summary
After a tooth is removed, the surrounding bone and gum tissue can shrink. Socket preservation places a bone graft in the extraction socket and covers it with a membrane to support healing before a dental implant is placed. This study will compare two membranes used with the same allogeneic bone graft. One group will receive a resorbable magnesium membrane (NOVAMag), and the other group will receive a non-resorbable polytetrafluoroethylene membrane (permamem). Participants who need a tooth extraction and later implant placement will be randomly assigned to one of the two groups. The extraction and grafting procedures will be standardized. Follow-up examinations will take place 7 days, 21 days, and 3 months after socket preservation. The study will assess gum healing and postoperative complications. Cone beam computed tomography scans obtained before extraction and at 3 months will be used to evaluate changes in alveolar bone volume. A bone sample will be collected from the treated site during the planned implant placement at 3 months for microscopic examination. The study aims to compare bone and soft tissue healing between the two membrane groups.
Official title: Comparative Evaluation of Bone and Soft Tissue Healing Following Alveolar Socket Preservation Using Maxgraft Plus With NOVAMag and Permamem Membranes
Key Details
Gender
All
Age Range
25 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-11-01
Completion Date
2028-07-31
Last Updated
2026-10-02
Healthy Volunteers
Yes
Interventions
NOVAMag Membrane
Placement of a resorbable magnesium barrier membrane over the grafted extraction socket during alveolar socket preservation.
permamem Membrane
Placement of a non-resorbable polytetrafluoroethylene barrier membrane over the grafted extraction socket during alveolar socket preservation.
Alveolar Socket Preservation With an Allogeneic Bone Graft
Atraumatic extraction, socket debridement and saline irrigation, followed by placement of an allogeneic bone graft. The grafted socket is covered with the membrane assigned to the participant's treatment group.
Locations (1)
School of Dental Medicine
Zagreb, City of Zagreb, Croatia