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RECRUITING
NCT07857044

Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities

Sponsor: Christina Berr. MD

View on ClinicalTrials.gov

Summary

Pulmonary vein isolation is an established intervention for atrial fibrillation. Patients with a paroxysmal atrial fibrillation have no or only few comorbidities and a good prognosis in respect to their atrial fibrillation. In contrast, patients with persistent atrial fibrillation often suffer from relevant comorbidities and recurrence of atrial fibrillation is common. Left-atrial fibrosis and its electrophysiological consequences are involved in the recurrence rate, but pathophysiological mechanisms are yet to be better characterized. The study investigates relevant comorbidities to elucidated their effect on atrial fibrosis and recurrence rates of atrial fibrillation. Furthermore, the investigators evaluate the prevalence of these comorbidities.

Official title: Left-atrial Fibrosis in Persistent Atrial Fibrillation, Sleep Apnoe and Primary Aldosteronism

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-03-31

Completion Date

2029-12-31

Last Updated

2026-10-05

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Screening on comorbidites

Patients with persistent atrial fibrillation that undergo ablation are screened for comorbidities

Locations (1)

University hospital Augsburg

Augsburg, Bavaria, Germany