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RECRUITING
NCT07858591

Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.

Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital

View on ClinicalTrials.gov

Summary

In terms of blood flow per unit of tissue, the retina is one of the tissues with the highest blood flow in the body. Parameters such as the thickness of the choroid layer, which plays a crucial role in maintaining normal eye function, the dimensions of the foveal avascular zone (FAZ) supplied by this layer, and retinal vascular networks can be measured using non-invasive methods. OCTA (Optical Coherence Tomography Angiography) is an imaging tool that enables the non-invasive assessment of retinal microvascular densities and the measurement of the foveal avascular zone's dimensions. Studies conducted to date indicate that retinal capillary vessels and the dimensions of the foveal avascular zone are affected in rheumatological diseases, especially associated with systemic inflammation. This study aims to compare retinal capillary vessel density and foveal avascular zone dimensions in patients with psoriatic arthritis against those in a healthy population and in patients with psoriasis who do not have psoriatic arthritis, utilizing the non-invasive method of optical coherence tomography angiography.

Official title: Evaluation of Retinal Capillary Vascular Structures and the Foveal Avascular Zone in Patients With Psoriatic Arthritis.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

135

Start Date

2026-09-01

Completion Date

2027-08-31

Last Updated

2026-10-13

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

OCTA-SCP

Vessel density of retinal superficial capillary plexus

DIAGNOSTIC_TEST

OCTA-DCP

Vessel density of retinal deep capillary plexus

DIAGNOSTIC_TEST

OCTA-RPC

Vessel density of retinal prepapillary capillaries

DIAGNOSTIC_TEST

OCTA-FAZ

FAZ essessment parameters

Locations (1)

University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital

Bursa, Yıldırım, Turkey (Türkiye)