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Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.
Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital
Summary
In terms of blood flow per unit of tissue, the retina is one of the tissues with the highest blood flow in the body. Parameters such as the thickness of the choroid layer, which plays a crucial role in maintaining normal eye function, the dimensions of the foveal avascular zone (FAZ) supplied by this layer, and retinal vascular networks can be measured using non-invasive methods. OCTA (Optical Coherence Tomography Angiography) is an imaging tool that enables the non-invasive assessment of retinal microvascular densities and the measurement of the foveal avascular zone's dimensions. Studies conducted to date indicate that retinal capillary vessels and the dimensions of the foveal avascular zone are affected in rheumatological diseases, especially associated with systemic inflammation. This study aims to compare retinal capillary vessel density and foveal avascular zone dimensions in patients with psoriatic arthritis against those in a healthy population and in patients with psoriasis who do not have psoriatic arthritis, utilizing the non-invasive method of optical coherence tomography angiography.
Official title: Evaluation of Retinal Capillary Vascular Structures and the Foveal Avascular Zone in Patients With Psoriatic Arthritis.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
135
Start Date
2026-09-01
Completion Date
2027-08-31
Last Updated
2026-10-13
Healthy Volunteers
Yes
Interventions
OCTA-SCP
Vessel density of retinal superficial capillary plexus
OCTA-DCP
Vessel density of retinal deep capillary plexus
OCTA-RPC
Vessel density of retinal prepapillary capillaries
OCTA-FAZ
FAZ essessment parameters
Locations (1)
University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, Yıldırım, Turkey (Türkiye)