Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT07859631
PHASE4

Ibuprofen Versus Dexketoprofen in Rib Fractures

Sponsor: Ankara City Hospital Bilkent

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare the pain-relieving effects of two different nonsteroidal anti-inflammatory drugs (NSAIDs), intravenous ibuprofen and intravenous dexketoprofen, in adults who present to the emergency department with isolated rib fractures. Patients with rib fractures confirmed by a computed tomography (CT) scan and experiencing moderate to severe pain will randomly receive either 800 mg of intravenous ibuprofen or 50 mg of intravenous dexketoprofen. The researchers will measure pain levels using a 100-mm Visual Analog Scale (VAS) before the treatment and at 30, 60, and 120 minutes after receiving the medication to evaluate which drug provides better pain relief. The study will also track how many patients require additional rescue pain medication and record any side effects that occur during the observation period.

Official title: Intravenous Ibuprofen Versus Dexketoprofen for Acute Pain Control in Isolated Rib Fractures: A Prospective, Randomized, Single-Blind Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

128

Start Date

2024-01-01

Completion Date

2024-05-25

Last Updated

2026-10-06

Healthy Volunteers

No

Conditions

Interventions

DRUG

Ibuprofen 800 mg

800 mg of intravenous ibuprofen in 150 mL of 0.9% sodium chloride over 5-10 minutes.

DRUG

Dexketoprofen 50 mg

50 mg of intravenous dexketoprofen in 150 mL of 0.9% sodium chloride over 5-10 minutes.

Locations (1)

Bilkent City Hospital

Ankara, Cankaya, Turkey (Türkiye)