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NOT YET RECRUITING
NCT07861074
PHASE2

A Clinical Trial Of Tulisokibart In Participants With Active, Non-Infectious Uveitis (MK-7240-019)

Sponsor: Merck Sharp & Dohme LLC

View on ClinicalTrials.gov

Summary

This trial will help researchers learn if tulisokibart, the trial medicine, can treat non-infectious intermediate, posterior, or panuveitis (NIIPPU) so that steroids can be given for a shorter period of time. In this trial, researchers will look at different doses (amounts) of tulisokibart. The goal of this trial is to learn if tulisokibart works better than placebo to increase the length of time until NIIPPU gets worse. A placebo looks like the trial medicine but has no medicine in it. Using a placebo helps researchers better understand the effects of the trial medicine.

Official title: A Phase 2b, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tulisokibart in Participants With Active Noninfectious Intermediate, Posterior, or Panuveitis

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

87

Start Date

2026-10-27

Completion Date

2032-04-06

Last Updated

2026-10-06

Healthy Volunteers

No

Interventions

DRUG

Tulisokibart

Subcutaneous (SC) administration

DRUG

Placebo

SC administration

DRUG

Background prednisone therapy

Oral administration