Clinical Research Directory

Key Inclusion Criteria: 1. Has a diagnosis of Graves' Disease for at least 4 months prior to the screening visit 2. Has thyroid-stimulating hormone receptor antibody (TRAb) level above the upper limit of normal at the screening visit 3. Euthyroid at the screening visit and at least 4 weeks prior to the screening visit as defined in the protocol 4. Body mass index (BMI) between 18.5 and 35.0 kg/m\^2 (inclusive) at the screen visit Key Exclusion Criteria: 1. Has history of hyperthyroidism not caused by Graves' disease (eg, toxic thyroid adenoma, multinodular goiter, amiodarone-induced) 2. Has active thyroid storm or is at current risk of thyroid storm, as assessed by the investigator at the screening visit 3. Has clinically significant cardiac abnormalities attributable to uncontrolled Graves' disease (eg, arrhythmias precipitated by thyrotoxicosis, thyrotoxic cardiomyopathy) 4. Has any infection requiring systemic therapy within the 4 weeks prior to the screening visit 5. Was hospitalized (ie, \>24 hours) for a reason within 30 days of the screening visit that presents any concern to the trial investigator 6. Has used or is using Levothyroxine (LT4) therapy at any dose within 6 weeks of the screening visit 7. Has history of Radioactive iodine (RAI) thyroid ablation or thyroidectomy Note: Other protocol defined Inclusion/Exclusion criteria apply