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NOT YET RECRUITING
NCT07862114
PHASE1

A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy Participants

Sponsor: GlaxoSmithKline

View on ClinicalTrials.gov

Summary

This study will look at how two commonly used medicines, omeprazole and cyclosporine, influence the way the body absorbs, processes, and eliminates velzatinib in healthy volunteers.

Official title: A Phase 1 Non-Randomized, Open-Label, Parallel-Group Study to Investigate the Effects of Coadministration of the Proton Pump Inhibitor Omeprazole or the P-gp/BCRP Inhibitor Cyclosporine on the Pharmacokinetics, Safety, and Tolerability of Velzatinib in Healthy Participants

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2026-10-16

Completion Date

2027-01-12

Last Updated

2026-10-07

Healthy Volunteers

Yes

Interventions

DRUG

Velzatinib

Velzatinib will be administered.

DRUG

Cyclosporine

Cyclosporine will be administered.

DRUG

Omeprazole

Omeprazole will be administered.