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A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy Participants
Sponsor: GlaxoSmithKline
Summary
This study will look at how two commonly used medicines, omeprazole and cyclosporine, influence the way the body absorbs, processes, and eliminates velzatinib in healthy volunteers.
Official title: A Phase 1 Non-Randomized, Open-Label, Parallel-Group Study to Investigate the Effects of Coadministration of the Proton Pump Inhibitor Omeprazole or the P-gp/BCRP Inhibitor Cyclosporine on the Pharmacokinetics, Safety, and Tolerability of Velzatinib in Healthy Participants
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2026-10-16
Completion Date
2027-01-12
Last Updated
2026-10-07
Healthy Volunteers
Yes
Interventions
Velzatinib
Velzatinib will be administered.
Cyclosporine
Cyclosporine will be administered.
Omeprazole
Omeprazole will be administered.