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RECRUITING
NCT07862257

Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery

Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

View on ClinicalTrials.gov

Summary

This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under general anesthesia. Cerebral regional oxygen saturation will be monitored using bilateral frontal near-infrared spectroscopy (NIRS), while respiratory parameters including tidal volume, respiratory rate, peak airway pressure, plateau pressure, positive end-expiratory pressure, and dynamic compliance will be recorded from the anesthesia ventilator. Measurements will be obtained at predefined time points before and after positioning the patient prone and after returning to the supine position at the end of surgery. No changes will be made to anesthesia, ventilation, medication doses, or surgical management for research purposes. All clinical care will be provided according to routine practice by the responsible anesthesia team. The study will investigate whether changes in respiratory mechanics during prone positioning are associated with changes in cerebral regional oxygen saturation.

Official title: Evaluation of the Relationship Between Changes in Pulmonary Mechanics and Ventilatory Energy Load and Cerebral Oxygenation During Lumbar Disc Surgery in the Prone Position

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-09-09

Completion Date

2027-01-30

Last Updated

2026-10-09

Healthy Volunteers

No

Interventions

PROCEDURE

Prone Positioning

Patients will be placed in the prone position as part of routine surgical care for lumbar disc surgery. The study will observe changes in respiratory mechanics and cerebral regional oxygen saturation before and after prone positioning. No positioning intervention will be assigned or modified for research purposes.

Locations (1)

Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital

Istanbul, Istanbul, Turkey (Türkiye)