Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparison of Post-Operative Sensitivity of 5th Genaration Bonding Agent With 8th Generation Bonding Agent in Class1 Composite Restoration
Sponsor: Rehman Medical Institute - RMI
Summary
The goal of this randomized clinical trial is to compare post-operative sensitivity after Class I composite restorations using 5th-generation and 8th-generation bonding agents in adults aged 18 to 50 years. The main question is whether the level of sensitivity differs between the two bonding agents. Participants will be randomly assigned to receive either a 5th-generation or an 8th-generation bonding agent during their composite restoration. Sensitivity will be measured using a 0-10 Visual Analogue Scale immediately after treatment, at 24 hours, and at 7 days after treatment.
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2026-03-01
Completion Date
2026-08-30
Last Updated
2026-10-07
Healthy Volunteers
No
Conditions
Interventions
5th generation bonding agent
A 5th-generation total-etch adhesive system will be used for bonding composite resin in Class I restorations. The enamel and dentin will be etched with phosphoric acid according to the manufacturer's instructions, followed by application of the bonding agent. The composite restoration will then be placed according to the standardized clinical protocol. Post-operative sensitivity will be assessed using a visual analogue scale (VAS) at the specified follow-up periods.
8th generation bonding agent
An 8th-generation self-etch adhesive system will be used for bonding composite resin in Class I restorations. The adhesive will be applied according to the manufacturer's instructions, followed by placement of the composite restoration using the standardized clinical protocol. Post-operative sensitivity will be assessed using a visual analogue scale (VAS) at the specified follow-up periods.
Locations (1)
Rehman College of Dentistry ,Peshawar, Pakistan
Peshawar, KPK, Pakistan