Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
NOT YET RECRUITING
NCT07862504

Cardiovascular Pre-participation Screening in Children and Adolescents

Sponsor: University of Sao Paulo

View on ClinicalTrials.gov

Summary

Sports participation is strongly encouraged in children and adolescents, but intense training at early ages may reveal hidden heart conditions that increase the risk of sudden cardiac death. Pre-participation evaluation aims to identify these conditions before sports practice. This observational study will evaluate children and adolescents enrolled in the São Paulo Olympic Program (Programa São Paulo Olímpico). All participants will undergo a structured medical interview, a standardized physical examination and a resting 12-lead electrocardiogram (ECG). Participants with borderline ECG findings, warning symptoms, abnormal physical examination findings or a suggestive personal or family history will also undergo a 3-minute step test (Harvard step test) with continuous ECG recording during exercise and recovery, in order to detect exercise-induced arrhythmias. The main goal is to estimate the prevalence of potentially pathological ECG findings in this population. The study will also describe warning signs in the medical history, abnormal physical examination findings, step test results, and the referrals and confirmed diagnoses during follow-up.

Official title: Cardiovascular Pre-participation Evaluation With Physical Examination, Resting Electrocardiogram and Step Test in Children and Adolescents of the São Paulo Olympic Program: a Prospective Observational Study

Key Details

Gender

All

Age Range

5 Years - 17 Years

Study Type

OBSERVATIONAL

Enrollment

334

Start Date

2027-02

Completion Date

2027-12-22

Last Updated

2026-10-07

Healthy Volunteers

Yes

Interventions

OTHER

Pre-participation clinical evaluation

Structured cardiovascular medical history and standardized physical examination.

DIAGNOSTIC_TEST

Diagnostic Test: Resting 12-lead electrocardiogram

Resting 12-lead electrocardiogram (ECG) analyzed independently by two blinded sports cardiologists.

DIAGNOSTIC_TEST

Diagnostic Test: Step test (Harvard step test)

3-minute continuous step test with electrocardiogram (ECG) recording during exercise and recovery, performed only in participants with borderline ECG findings, warning symptoms, abnormal physical examination or suggestive personal or family history.

Locations (1)

Heart Institute

São Paulo, São Paulo, Brazil