Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012)
Sponsor: Merck Sharp & Dohme LLC
Summary
Researchers are looking for new treatments for pain. The goal of this trial is to learn if MK-6916 changes what happens to the midazolam and rosuvastatin in healthy participants' bodies. Researchers will compare the amount of midazolam and rosuvastatin in a participant's body over time when they are given with and without MK-6916.
Official title: A 2-period Study to Evaluate the Effects of Multiple Oral Doses of MK-6916 on the Single-dose Pharmacokinetics of Midazolam and Rosuvastatin
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
18
Start Date
2026-11-30
Completion Date
2027-02-19
Last Updated
2026-10-07
Healthy Volunteers
Yes
Conditions
Interventions
Midazolam
Administered orally on Day 1 of Period 1 and on Days 2 and 14 of Period 2.
Rosuvastatin
Administered orally on Day 1 of Period 1 and Day 14 of Period 2.
MK-6916
Administered orally once every 12 hours on Days 1 through 18 in Period 2.