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NOT YET RECRUITING
NCT07862686
NA

Hyaluronic Acid Combined With Xenograft Versus Xenograft Alone in Immediate Implant Placement

Sponsor: Cairo University

View on ClinicalTrials.gov

Summary

This randomized controlled clinical trial aims to compare the clinical and radiographic outcomes of immediate implant placement using xenograft combined with hyaluronic acid versus xenograft alone in the esthetic zone. Patients requiring extraction of a non-restorable tooth followed by immediate implant placement will be randomly allocated to two groups. In the intervention group, the jumping gap between the implant and facial bone wall will be grafted with xenograft combined with hyaluronic acid, while in the control group, xenograft alone will be used. The primary outcome is the radiographic change in the labio-palatal ridge width. Secondary outcomes include pink esthetic score, implant stability, crestal bone loss, and the amount of bone labial to the implant. Patients will be followed for up to 12 months postoperatively.

Official title: Clinical and Radiographic Evaluation of Hyaluronic Acid Combined With Xenograft Versus Xenograft Alone in Immediate Implant Placement in the Esthetic Zone: A Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2026-09

Completion Date

2027-09

Last Updated

2026-10-07

Healthy Volunteers

No

Interventions

PROCEDURE

Immediate implant placement

Immediate implant placement following atraumatic tooth extraction in the esthetic zone.

BIOLOGICAL

Xenograft

Xenograft bone graft material used to fill the jumping gap around the immediately placed implant

DRUG

Hyaluronic Acid (0.2%)

Hyaluronic acid gel (0.2%) combined with xenograft for filling the jumping gap around the immediately placed implant.

Locations (1)

Faculty of Dentistry, Cairo University

Cairo, Egypt