Clinical Research Directory

Inclusion Criteria: * Age 40-75 years * Underwent unilateral or bilateral nerve-sparing radical prostatectomy between 1 and 3 years prior to the study * Good erectile function prior to surgery (IIEF-EF score ≥ 22) * Erectile dysfunction at inclusion with an IIEF-EF score \< 22 without aids * Acceptance of a pause in other treatments for erectile dysfunction from 4 weeks before baseline (wash-out) until the 1-month follow-up after the last injection * In a stable relationship lasting at least 6 months with a desire for sexual activity * Able to understand and accept the study protocol Exclusion Criteria: * Known psychiatric, neurological and/or endocrinological disease requiring medication (including hypogonadism with total testosterone \<12 nmol/l). * Severe urinary incontinence preventing sexual activity (assessed by a physician at inclusion) * Clinical or biochemical recurrence of prostate cancer * Other surgery or radiation therapy in the pelvic region * Severe cardiac disease in the form of unstable angina, NYHA class \>II heart failure, uncontrolled arrhythmia, or severe symptomatic and/or significant valvular disease * Use of anti-androgen medication * Peyronie's disease and/or previous episodes of priapism * Excessive alcohol consumption (more than 21 units per week)