Clinical Research Directory

Inclusion Criteria: The study population comprises infants who are at risk of motor or other developmental delay. "At-risk" is defined as having been admitted to the NICU admission and qualifying for Early Childhood Clinic (NICU high-risk follow up clinic) or Early Intervention due to: * BW \<1500 grams OR * Disorders of the central nervous system * Brain injury (including but not limited to extra axial hemorrhage, any grade intraventricular or intraparenchymal hemorrhage, stroke, hypoxic ischemic encephalopathy (HIE), meningitis) * HIE includes mild, moderate, severe exam on modified Sarnat exam, both cooled and non-cooled * includes "at risk for HIE" with 10-minute Apgar \<7 plus pH\<7.15 or base deficit \>/=12. * Brain developmental abnormalities (hydrocephalus, microcephaly, cortical dysgenesis) * Cramped synchronous movements at term PMA (post-menstrual age) OR * Bronchopulmonary dysplasia (BPD) defined as need for respiratory support at 36 weeks postmenstrual age in an infant born at \<32 weeks of gestation. AND \- Medically stable (as determined by their neonatologist) AND able to begin study procedures between 34-48 weeks PMA. Exclusion Criteria: * Open wounds, skin condition precluding sensor placement * Immune deficiencies requiring protective isolation * Limb reduction defects * Followed primarily in another clinic (including but not limited to meningomyelocele and related conditions/trisomy 21) * Bleeding disorders or ongoing need for anticoagulation * Palliative or hospice care (for life limiting conditions including, but not limited to trisomy 18, 13) * Known visual impairment at the time of enrollment * DCFS custody * No English-speaking caregivers * Any other condition that would preclude participation in the study, as determined by the PI * Previously enrolled in competing randomized trial with developmental outcome variables