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Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults
Sponsor: University of Northern Iowa
Summary
This study examined whether short-term creatine supplementation affects cognitive function in healthy young adults. Participants were randomly assigned to take either creatine monohydrate or a placebo for 10 days. Participants took 30 grams per day, divided into six 5-gram doses. Before and after the supplementation period, participants completed cognitive tests designed to assess areas such as memory, attention, reaction time, and processing speed. Participants also completed a 30-minute mentally challenging Stroop task, and brain oxygenation was measured during cognitive testing using functional near-infrared spectroscopy (fNIRS). The purpose of the study was to determine whether 10 days of high-dose creatine supplementation improves cognitive performance compared with placebo following a mentally challenging task.
Official title: The Effects of Short-Term, High-Dosage Creatine Supplementation on Cognitive Measures Following Mental Fatigue in Healthy Young Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2024-04-10
Completion Date
2024-12-03
Last Updated
2026-10-09
Healthy Volunteers
Yes
Interventions
Creatine Monohydrate
Participants consumed 30 g/day of creatine monohydrate (Creapure®; AlzChem Trostberg GmbH, Germany) for 10 consecutive days. The daily dose was divided into six 5-g doses consumed throughout the day and mixed with food or water. Each 5-g dose was provided in an individual bag.
Maltodextrin Placebo
Participants consumed 30 g/day of maltodextrin (Dry Maltodextrin; Cargill, Minnesota, USA) for 10 consecutive days. The daily dose was divided into six 5-g doses consumed throughout the day and mixed with food or water. The placebo was provided in individual bags and was similar to the creatine intervention in taste, color, texture, and appearance.
Locations (1)
University of Northern Iowa
Cedar Falls, Iowa, United States