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Exploration of Tolerability and Dose Responses for a Yeast-based Probiotic
Sponsor: Colorado State University
Summary
The purpose of this study is to evaluate the tolerability and efficacy of a yeast-based dietary supplement on gastrointestinal, mental, and skin health. Yeasts are naturally present on fruits and plants, and are used to bake bread, beer and wine. Some of these yeasts are commonly consumed and may actually benefit your gut health. The supplemental yeast could strengthen your gut lining or help good bacteria in your gut grow better. In this study, we will look at how two doses of a yeast-baaed supplement impacts your gut health, your bowel movement consistency, your and mental health. the study will last 17 weeks and consist of 7 clinic visits (1 screening visit and 6 test visits).
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-11-01
Completion Date
2028-03-01
Last Updated
2026-10-09
Healthy Volunteers
Yes
Conditions
Interventions
9.9 x 10^7 Pichia kluyveri PK88
9.9 x 10\^7 Pichia kluyveri in microcrystalline cellulose and hypromellose
1 x 10^8 Pichia kluyveri PK88
1 x 10\^8 Pichia kluyveri in microcrystalline cellulose and hypromellose
Placebo
Placebo - cellulose and hypromellose
Locations (1)
Colorado State University
Fort Collins, Colorado, United States