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ENROLLING BY INVITATION
NCT07867587
NA

Radiological Intervention for Childhood Extra-Hepatic Portal Vein Obstruction

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

This study evaluates the safety and effectiveness of percutaneous portal vein recanalization (PVR) with stent placement, with or without transjugular intrahepatic portosystemic shunt (TIPS), in restoring portal flow and improving clinical outcomes in children and adolescents with chronic extrahepatic portal vein obstruction (EHPVO). The trial will assess technical feasibility, patency rates, and the reduction of complications such as variceal bleeding, ascites, and thrombocytopenia.

Official title: Radiological Intervention for Chronic Extra-Hepatic Portal Vein Obstruction in Children and Adolescents: Technical Feasibility and Early Clinical Outcome.

Key Details

Gender

All

Age Range

2 Years - 17 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2025-10-30

Completion Date

2027-10-30

Last Updated

2026-10-09

Healthy Volunteers

No

Interventions

DEVICE

Portal Vein Recanalization and Stenting

Percutaneous portal vein recanalization and stenting using metallic uncovered stents, with or without TIPS, performed using a multi-access strategies (access needles, guidewires and catheters) under general anesthesia to restore portal flow

Locations (1)

Ain Shams University Hospitals

Cairo, Egypt