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Low Dose Induction for Pediatric Acute Myeloid Leukemia Patients
Sponsor: Azza Shibl Sayed
Summary
the standard induction treatment for pediatric acute myeloid leukemia has high early morbidity and mortality that jeopardize the outcome especially in developing countries. SIOP recommended lower dose induction synergistic G- CSF to minimize these unwanted toxicities. the study aimed at minimizing the toxicities during induction without jeopardizing the survival.
Official title: Outcome of Pediatric Patients With Acute Myeloid Leukemia Treated According to SIOP Guidelines in Developing Countries
Key Details
Gender
All
Age Range
Any - 18 Years
Study Type
INTERVENTIONAL
Enrollment
33
Start Date
2022-07-28
Completion Date
2030-07
Last Updated
2026-10-09
Healthy Volunteers
No
Interventions
Low dose Ara C/ anthracycline combined with GCSF
low dose mitothantrone and Ara C concurrently with G-CSF during induction treatment of pediatric acute myeloid leukemia to be compared with the standard induction
Locations (2)
South Egypt Cancer Institute, Assiut Univeristy
Asyut, Asyut Governorate, Egypt
South Egypt Cancer Institute, Assiut Univeristy
Asyut, Asyut Governorate, Egypt