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Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters in COPD
Sponsor: Júnea Regina Pires Drews
Summary
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent respiratory symptoms and systemic inflammation. Dietary fiber intake has been associated with beneficial effects on gut microbiota composition and systemic inflammatory markers. This study aims to evaluate the effects of dietary fiber supplementation on systemic inflammation and clinical parameters in patients with COPD through a randomized, double-blind, placebo-controlled trial.
Official title: Efeito Da Suplementação Dietética De Fibras Sobre Inflamação Sistêmica E Parâmetros Clínicos Na DPOC: Ensaio Clínico Randomizado, Duplo-Cego E Controlado Por Placebo
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-11
Completion Date
2027-07
Last Updated
2026-10-14
Healthy Volunteers
No
Conditions
Interventions
Dietary Fiber Supplementation
Daily oral supplementation of dietary fiber administered for the intervention period alongside standard medical care.
Placebo Control
Daily oral administration of an isocaloric placebo, identical in appearance, taste, and packaging to the active fiber supplement.
Locations (1)
Hospital das Clínicas da UFMG - Ambulatório de Doenças Pulmonares Intersticiais
Belo Horizonte, Minas Gerais, Brazil