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RECRUITING
NCT07868419
PHASE3

Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) Tablets

Sponsor: Trevi Therapeutics

View on ClinicalTrials.gov

Summary

The primary purpose is to evaluate the safety and efficacy of NAL ER for the treatment of chronic cough in participants with IPF.

Official title: A Randomized, Double-Blind, Placebo-Controlled Twelve-Week Fixed-Dose Study to Evaluate the Efficacy and Safety of Nalbuphine Extended-Release Tablets for the Treatment of Chronic Cough in Participants With Idiopathic Pulmonary Fibrosis

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

201

Start Date

2026-09-30

Completion Date

2027-10

Last Updated

2026-10-09

Healthy Volunteers

No

Interventions

DRUG

NAL ER

Oral tablets

DRUG

Placebo

Oral tablets

Locations (4)

Premier Medical Associates, LLC

Wilmington, Delaware, United States

Essential Health and Research Services

North Miami Beach, Florida, United States

American Health Research - Charlotte Location

Charlotte, North Carolina, United States

Hillcroft Medical Clinic

Sugar Land, Texas, United States