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Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Sponsor: October 6 University
Summary
* Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited. * Adding topical exosomes via laser-assisted drug delivery may enhance scar remodeling and skin elasticity compared with HA, whereas HA provides superior hydration, supporting individualized treatment selection based on therapeutic goals. These findings are preliminary and require confirmation in larger studies.
Official title: A Split Face Comparative Study Between Fractional Carbon Dioxide Laser And Exosomes Versus Fractional Carbon Dioxide Laser And Skin Booster In The Treatment Of Post-Acne Scars
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-06-01
Completion Date
2025-09-01
Last Updated
2026-10-09
Healthy Volunteers
No
Conditions
Interventions
Fractional co2 laser
Transepidermal drug delivery through fractional co2 laser
Exosomes
Topical application of exosomes immediately following fractional carbon dioxide (CO2) laser therapy.
Hyaluronic Acid skin booster
Hyaluronic acid based skin booster applied after fractional co2 laser immediately
Locations (1)
October 6 University
Giza, Egypt