Clinical Research Directory

Inclusion Criteria: * Age ≥18 years * Presence of ≥1 de novo coronary lesion treated with successful DCB-only PCI * No stent implantation within the target segment during the index procedure * Diagnostic-quality CCTA performed before the index PCI and/or diagnostic-quality follow-up CCTA performed 3 to 12 months after DCB angioplasty * Adequate visualization of the target vessel and treated segment on the available CCTA examination(s) to permit quantitative analysis * Availability of the index PCI angiogram and sufficient procedural data to identify the DCB-treated segment * Successful index PCI with an acceptable final angiographic result and stable clinical status at discharge Exclusion Criteria: * In-stent restenosis as the target lesion * Bailout or planned stent implantation within the target segment during the index procedure * CCTA of insufficient diagnostic quality for quantitative analysis of the target segment because of severe calcification, motion artifact, misregistration, or other technical limitations * Follow-up CCTA performed outside the prespecified time window * Target-lesion revascularization before the scheduled follow-up CCTA, precluding paired imaging assessment of the untreated follow-up state * Inability to reliably identify and match the DCB-treated coronary segment between the index angiogram and baseline/follow-up CCTA * Life expectancy less than 12 months from a non-cardiac cause