Clinical Research Directory

Inclusion Criteria: * Aged 18 to 45 years * Assigned female at birth * Experienced a sexual assault within the previous 120 hours and able to complete an in-person study visit within 120 hours of the assault * Able to read and speak English * Able to provide informed consent Exclusion Criteria: * Pregnant or currently breastfeeding * Currently taking an estrogen-containing medication * Current or prior diagnosis of hypertension * Use of anticoagulant medications (e.g. aspirin, heparin, warfarin, enoxaparin, dalteparin, tinzaparin, apixaban, rivaroxaban, dabigatran, edoxaban) * Current or prior cardiomyopathy; history of heart attack or heart valve disease * History of deep venous thrombosis or pulmonary embolism, or genetic predisposition to clots (thrombophilia) * Sickle cell disease * History of stroke * Migraines with aura * Vascular disease due to diabetes, or diabetes of more than 20 years duration * Chronic kidney disease (including nephrotic syndrome or dialysis) * Acute hepatitis; history of liver tumors * History of cholestasis (unless pregnancy-related only) * Gallbladder disease (unless treated by cholecystectomy) * History of systemic lupus erythematosus * History of breast or endometrial cancer * Opioid use exceeding 30 mg daily oral morphine equivalents per day * Smokes more than 15 cigarettes per day