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THiamine for Recovery In Vulnerable Early-life Infections
Sponsor: Milton S. Hershey Medical Center
Summary
To determine if the addition of thiamine to standard-of-care treatment will improve neurodevelopmental outcomes for infants with meningitis or bacteremia
Key Details
Gender
All
Age Range
Any - 12 Months
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2026-12-01
Completion Date
2031-11-30
Last Updated
2026-10-09
Healthy Volunteers
No
Conditions
Interventions
thiamine hydrochloride 100 mg
Patients will receive 100mg of IV thiamine in addition to standard-of-care treatment, once a day for three days
Placebo
Participants will receive placebo in addition to standard-of-care treatment
Locations (2)
Boston Children's Hospital
Boston, Massachusetts, United States
Penn State Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States