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Obesity and Clinical and Cytokine Responses to Periodontal Therapy
Sponsor: Emine Çifcibaşı
Summary
This prospective controlled clinical study included 80 participants allocated into four groups according to body mass index (BMI) and periodontal status: obese periodontitis, normal-weight periodontitis, obese periodontally healthy, and normal-weight periodontally healthy. Clinical periodontal parameters and salivary levels of IL-6, IL-10, TNF-α, and adiponectin were assessed at baseline in all participants. Individuals with periodontitis received non-surgical periodontal therapy, and clinical and biochemical evaluations were repeated after 3 months.
Official title: Evaluation of Biochemical and Periodontal Parameters in Obese Individuals
Key Details
Gender
All
Age Range
25 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2015-01-06
Completion Date
2015-07-07
Last Updated
2026-10-09
Healthy Volunteers
Yes
Interventions
Scaling and Root Planing (SRP)
Non-surgical periodontal therapy consisting of scaling and root planing was performed using hand and ultrasonic instruments under local anesthesia when necessary. Supra- and subgingival plaque and calculus were removed. Oral hygiene instructions were provided to all participants. Treatment was completed within the standard clinical protocol.